Use when design is complete and you need detailed implementation tasks for engineers with zero codebase context - creates comprehensive implementation plans with exact file paths, complete code examples, and verification steps assuming engineer has minimal domain knowledge
This skill provides symbol-level code understanding and navigation using Language Server Protocol (LSP). Enables IDE-like capabilities for finding symbols, tracking references, and making precise code edits at the symbol level.
Personalize COG for your workflow - creates profile, interests, and watchlist files with guided setup (run this first!)
Tauri framework for building cross-platform desktop and mobile apps. Use for desktop app development, native integrations, Rust backend, and web-based UIs.
Review code using Linus Torvalds' "good taste" philosophy. Eliminates defensive code, special cases, and deep nesting. Use when reviewing code quality, refactoring, or checking for code smells.
Execute Codex CLI for code analysis, refactoring, and automated code changes. Use when you need to delegate complex code tasks to Codex AI with file references (@syntax) and structured output.
Retrieval-augmented generation (RAG) skill for the D&D 5e System Reference Document (SRD). Use when answering questions about D&D 5e core rules, spells, combat, equipment, conditions, monsters, and other SRD content. This skill provides agentic search-based access to the SRD split into page-range markdown files.
Digital pathology image processing toolkit for whole slide images (WSI). Use this skill when working with histopathology slides, processing H&E or IHC stained tissue images, extracting tiles from gigapixel pathology images, detecting tissue regions, segmenting tissue masks, or preparing datasets for computational pathology deep learning pipelines. Applies to WSI formats (SVS, TIFF, NDPI), tile-based analysis, and histological image preprocessing workflows.
Cheminformatics toolkit for fine-grained molecular control. SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure search, 2D/3D generation, similarity, reactions. For standard workflows with simpler interface, use datamol (wrapper around RDKit). Use rdkit for advanced control, custom sanitization, specialized algorithms.
Quantum computing framework for building, simulating, optimizing, and executing quantum circuits. Use this skill when working with quantum algorithms, quantum circuit design, quantum simulation (noiseless or noisy), running on quantum hardware (Google, IonQ, AQT, Pasqal), circuit optimization and compilation, noise modeling and characterization, or quantum experiments and benchmarking (VQE, QAOA, QPE, randomized benchmarking).
Keeps IdeaVim documentation in sync with code changes. Use this skill when you need to verify documentation accuracy after code changes, or when checking if documentation (in doc/, README.md, CONTRIBUTING.md) matches the current codebase. The skill can work bidirectionally - from docs to code verification, or from code changes to documentation updates.
Write docstrings for PyTorch functions and methods following PyTorch conventions. Use when writing or updating docstrings in PyTorch code.
This skill should be used when converting academic papers into promotional and presentation formats including interactive websites (Paper2Web), presentation videos (Paper2Video), and conference posters (Paper2Poster). Use this skill for tasks involving paper dissemination, conference preparation, creating explorable academic homepages, generating video abstracts, or producing print-ready posters from LaTeX or PDF sources.
Create and manage Claude Code skills in HASH repository following Anthropic best practices. Use when creating new skills, modifying skill-rules.json, understanding trigger patterns, working with hooks, debugging skill activation, or implementing progressive disclosure. Covers skill structure, YAML frontmatter, trigger types (keywords, intent patterns), UserPromptSubmit hook, and the 500-line rule. Includes validation and debugging with SKILL_DEBUG. Examples include rust-error-stack, cargo-dependencies, and rust-documentation skills.
Primary Python tool for 40+ bioinformatics services. Preferred for multi-database workflows: UniProt, KEGG, ChEMBL, PubChem, Reactome, QuickGO. Unified API for queries, ID mapping, pathway analysis. For direct REST control, use individual database skills (uniprot-database, kegg-database).
Write automated tests for features, validate functionality against acceptance criteria, and ensure code coverage. Use when writing test code, verifying functionality, or adding test coverage to existing code.
PDF generation toolkit. Create invoices, reports, certificates, forms, charts, tables, barcodes, QR codes, Canvas/Platypus APIs, for professional document automation.
Search arXiv preprint repository for papers in physics, mathematics, computer science, quantitative biology, and related fields
Use when reviewing pull requests with comprehensive code analysis, incremental or full review options, and constructive feedback - provides thorough code reviews with severity ratings
Query and analyze SEC filings and financial statements using EdgarTools. Get company data, filings, XBRL financials, and perform multi-company analysis.
Create hierarchical project plans optimized for solo agentic development. Use when planning projects, phases, or tasks that Claude will execute. Produces Claude-executable plans with verification criteria, not enterprise documentation. Handles briefs, roadmaps, phase plans, and context handoffs.
Access Human Metabolome Database (220K+ metabolites). Search by name/ID/structure, retrieve chemical properties, biomarker data, NMR/MS spectra, pathways, for metabolomics and identification.
Framework for computational fluid dynamics simulations using Python. Use when running fluid dynamics simulations including Navier-Stokes equations (2D/3D), shallow water equations, stratified flows, or when analyzing turbulence, vortex dynamics, or geophysical flows. Provides pseudospectral methods with FFT, HPC support, and comprehensive output analysis.
Primary Python toolkit for molecular biology. Preferred for Python-based PubMed/NCBI queries (Bio.Entrez), sequence manipulation, file parsing (FASTA, GenBank, FASTQ, PDB), advanced BLAST workflows, structures, phylogenetics. For quick BLAST, use gget. For direct REST API, use pubmed-database.
Capture solved problems as categorized documentation with YAML frontmatter for fast lookup
Generate or edit images using AI models (FLUX, Gemini). Use for scientific illustrations, diagrams, schematics, infographics, concept visualizations, and artistic images. Supports image editing to modify existing images (change colors, add/remove elements, style transfer). Useful for figures, posters, and visual explanations.
Comprehensive toolkit for protein language models including ESM3 (generative multimodal protein design across sequence, structure, and function) and ESM C (efficient protein embeddings and representations). Use this skill when working with protein sequences, structures, or function prediction; designing novel proteins; generating protein embeddings; performing inverse folding; or conducting protein engineering tasks. Supports both local model usage and cloud-based Forge API for scalable inference.
Run SQL queries against the WordPress development database. Use when querying database tables, inspecting Simple History events, checking WordPress data, or debugging database issues.
CLI/Python toolkit for rapid bioinformatics queries. Preferred for quick BLAST searches. Access to 20+ databases: gene info (Ensembl/UniProt), AlphaFold, ARCHS4, Enrichr, OpenTargets, COSMIC, genome downloads. For advanced BLAST/batch processing, use biopython. For multi-database integration, use bioservices.
Execute Gemini CLI for AI-powered code analysis and generation. Use when you need to leverage Google's Gemini models for complex reasoning tasks.
Interactive scientific and statistical data visualization library for Python. Use when creating charts, plots, or visualizations including scatter plots, line charts, bar charts, heatmaps, 3D plots, geographic maps, statistical distributions, financial charts, and dashboards. Supports both quick visualizations (Plotly Express) and fine-grained customization (graph objects). Outputs interactive HTML or static images (PNG, PDF, SVG).
Autonomous biomedical AI agent framework for executing complex research tasks across genomics, drug discovery, molecular biology, and clinical analysis. Use this skill when conducting multi-step biomedical research including CRISPR screening design, single-cell RNA-seq analysis, ADMET prediction, GWAS interpretation, rare disease diagnosis, or lab protocol optimization. Leverages LLM reasoning with code execution and integrated biomedical databases.
Build Shopify applications, extensions, and themes using GraphQL/REST APIs, Shopify CLI, Polaris UI components, and Liquid templating. Capabilities include app development with OAuth authentication, checkout UI extensions for customizing checkout flow, admin UI extensions for dashboard integration, POS extensions for retail, theme development with Liquid, webhook management, billing API integration, product/order/customer management. Use when building Shopify apps, implementing checkout customizations, creating admin interfaces, developing themes, integrating payment processing, managing store data via APIs, or extending Shopify functionality.
Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery: SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conformers, parallel processing. Returns native rdkit.Chem.Mol objects. For advanced control or custom parameters, use rdkit directly.
Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.
Use when users need to debug, modify, or extend the code-forge application's CLI commands, argument parsing, or CLI behavior. This includes adding new commands, fixing CLI bugs, updating command options, or troubleshooting CLI-related issues.
Comprehensive Python library for astronomy and astrophysics. This skill should be used when working with astronomical data including celestial coordinates, physical units, FITS files, cosmological calculations, time systems, tables, world coordinate systems (WCS), and astronomical data analysis. Use when tasks involve coordinate transformations, unit conversions, FITS file manipulation, cosmological distance calculations, time scale conversions, or astronomical data processing.
Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis.
Comprehensive healthcare AI toolkit for developing, testing, and deploying machine learning models with clinical data. This skill should be used when working with electronic health records (EHR), clinical prediction tasks (mortality, readmission, drug recommendation), medical coding systems (ICD, NDC, ATC), physiological signals (EEG, ECG), healthcare datasets (MIMIC-III/IV, eICU, OMOP), or implementing deep learning models for healthcare applications (RETAIN, SafeDrug, Transformer, GNN).
Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for large-scale datasets.
Use to manage pricing, packaging, and approval workflows for renewal negotiations.
Work with MongoDB (document database, BSON documents, aggregation pipelines, Atlas cloud) and PostgreSQL (relational database, SQL queries, psql CLI, pgAdmin). Use when designing database schemas, writing queries and aggregations, optimizing indexes for performance, performing database migrations, configuring replication and sharding, implementing backup and restore strategies, managing database users and permissions, analyzing query performance, or administering production databases.
Claude Code plugin enforcing operational guidelines, terse responses, sequential execution, and no destructive operations without confirmation.
NGS analysis toolkit. BAM to bigWig conversion, QC (correlation, PCA, fingerprints), heatmaps/profiles (TSS, peaks), for ChIP-seq, RNA-seq, ATAC-seq visualization.
Create beautiful, accessible user interfaces with shadcn/ui components (built on Radix UI + Tailwind), Tailwind CSS utility-first styling, and canvas-based visual designs. Use when building user interfaces, implementing design systems, creating responsive layouts, adding accessible components (dialogs, dropdowns, forms, tables), customizing themes and colors, implementing dark mode, generating visual designs and posters, or establishing consistent styling patterns across applications.
Collection of AWS development skills covering CDK infrastructure as code, cost optimization, and serverless/event-driven architectures with integrated MCP servers.
Complete API integration guide for Shopify including GraphQL Admin API, REST Admin API, Storefront API, Ajax API, OAuth authentication, rate limiting, and webhooks. Use when making API calls to Shopify, authenticating apps, fetching product/order/customer data programmatically, implementing cart operations, handling webhooks, or working with API version 2025-10. Requires fetch or axios for JavaScript implementations.
专业的比特币钱包连接技能，支持btc-connect core、react、vue包在React、Vue、Next.js、Nuxt 3项目中的完整集成，包含UniSat和OKX钱包适配、网络切换功能、SSR环境配置、统一Hook API和v0.5.0最新特性
Generate typed TypeScript SDKs for AI agents to interact with MCP servers. Converts verbose JSON-RPC curl commands to clean function calls (docs.createDocument() vs curl). Auto-detects MCP tools from server modules, generates TypeScript types and client methods, creates runnable example scripts. Use when: building MCP-enabled applications, need typed programmatic access to MCP tools, want Claude Code to manage apps via scripts, eliminating manual JSON-RPC curl commands, validating MCP inputs/outputs, or creating reusable agent automation.
Access European Nucleotide Archive via API/FTP. Retrieve DNA/RNA sequences, raw reads (FASTQ), genome assemblies by accession, for genomics and bioinformatics pipelines. Supports multiple formats.
Manage BAP (Bitcoin Attestation Protocol) identity files using bap-cli. This skill should be used when users need to create, decrypt, list, or extract BAP identity backups, work with .bep encrypted files, or generate test fixtures for Playwright tests involving BAP identities.
Execute structured task plans with status tracking. Use when the user provides a plan file path in the format `plans/{current-date}-{task-name}-{version}.md` or explicitly asks you to execute a plan file.
Access NCBI GEO for gene expression/genomics data. Search/download microarray and RNA-seq datasets (GSE, GSM, GPL), retrieve SOFT/Matrix files, for transcriptomics and expression analysis.
Query NCBI Gene via E-utilities/Datasets API. Search by symbol/ID, retrieve gene info (RefSeqs, GO, locations, phenotypes), batch lookups, for gene annotation and functional analysis.
Process and generate multimedia content using Google Gemini API. Capabilities include analyze audio files (transcription with timestamps, summarization, speech understanding, music/sound analysis up to 9.5 hours), understand images (captioning, object detection, OCR, visual Q&A, segmentation), process videos (scene detection, Q&A, temporal analysis, YouTube URLs, up to 6 hours), extract from documents (PDF tables, forms, charts, diagrams, multi-page), generate images (text-to-image, editing, composition, refinement). Use when working with audio/video files, analyzing images or screenshots, processing PDF documents, extracting structured data from media, creating images from text prompts, or implementing multimodal AI features. Supports multiple models (Gemini 2.5/2.0) with context windows up to 2M tokens.
Optimize provider selection, routing, and credit usage across 150+ enrichment sources for company/contact intelligence.
Convert PyTorch AT_DISPATCH macros to AT_DISPATCH_V2 format in ATen C++ code. Use when porting AT_DISPATCH_ALL_TYPES_AND*, AT_DISPATCH_FLOATING_TYPES*, or other dispatch macros to the new v2 API. For ATen kernel files, CUDA kernels, and native operator implementations.
Systematically evaluate code changes for security, correctness, performance, and spec alignment. Use when reviewing PRs, assessing code quality, or verifying implementation against requirements.
Manage Model Context Protocol (MCP) servers - discover, analyze, and execute tools/prompts/resources from configured MCP servers. Use when working with MCP integrations, need to discover available MCP capabilities, filter MCP tools for specific tasks, execute MCP tools programmatically, access MCP prompts/resources, or implement MCP client functionality. Supports intelligent tool selection, multi-server management, and context-efficient capability discovery.
Write Ruby and Rails code in DHH's distinctive 37signals style. Use this skill when writing Ruby code, Rails applications, creating models, controllers, or any Ruby file. Triggers on Ruby/Rails code generation, refactoring requests, code review, or when the user mentions DHH, 37signals, Basecamp, HEY, or Campfire style. Embodies REST purity, fat models, thin controllers, Current attributes, Hotwire patterns, and the "clarity over cleverness" philosophy.
Transform, clean, reshape, and preprocess data using pandas and numpy. Works with ANY LLM provider (GPT, Gemini, Claude, etc.).
Generate structured task lists from specs or requirements. IMPORTANT: After completing ANY spec via ExitSpecMode, ALWAYS ask the user: "Would you like me to generate a task list for this spec?" Use when user confirms or explicitly requests task generation from a plan/spec/PRD.
Expert in React Native native modules, bridging JavaScript and native code, writing custom native modules, using Turbo Modules, Fabric, JSI, autolinking, module configuration, iOS Swift/Objective-C modules, Android Kotlin/Java modules. Activates for native module, native code, bridge, turbo module, JSI, fabric, autolinking, custom native module, ios module, android module, swift, kotlin, objective-c, java native code.
This skill should be used when working with single-cell omics data analysis using scvi-tools, including scRNA-seq, scATAC-seq, CITE-seq, spatial transcriptomics, and other single-cell modalities. Use this skill for probabilistic modeling, batch correction, dimensionality reduction, differential expression, cell type annotation, multimodal integration, and spatial analysis tasks.
Process-based discrete-event simulation framework in Python. Use this skill when building simulations of systems with processes, queues, resources, and time-based events such as manufacturing systems, service operations, network traffic, logistics, or any system where entities interact with shared resources over time.
Package entire code repositories into single AI-friendly files using Repomix. Capabilities include pack codebases with customizable include/exclude patterns, generate multiple output formats (XML, Markdown, plain text), preserve file structure and context, optimize for AI consumption with token counting, filter by file types and directories, add custom headers and summaries. Use when packaging codebases for AI analysis, creating repository snapshots for LLM context, analyzing third-party libraries, preparing for security audits, generating documentation context, or evaluating unfamiliar codebases.
Diffusion-based molecular docking. Predict protein-ligand binding poses from PDB/SMILES, confidence scores, virtual screening, for structure-based drug design. Not for affinity prediction.
Molecular machine learning toolkit. Property prediction (ADMET, toxicity), GNNs (GCN, MPNN), MoleculeNet benchmarks, pretrained models, featurization, for drug discovery ML.
Laboratory automation toolkit for controlling liquid handlers, plate readers, pumps, heater shakers, incubators, centrifuges, and analytical equipment. Use this skill when automating laboratory workflows, programming liquid handling robots (Hamilton STAR, Opentrons OT-2, Tecan EVO), integrating lab equipment, managing deck layouts and resources (plates, tips, containers), reading plates, or creating reproducible laboratory protocols. Applicable for both simulated protocols and physical hardware control.
This skill should be used when managing the file-based todo tracking system in the todos/ directory. It provides workflows for creating todos, managing status and dependencies, conducting triage, and integrating with slash commands and code review processes.
Guide for researching SQL syntax and behavior for database backends. Use when you need to research how a SQL function, command, or feature works in a specific database before implementing it in dbplyr.
Use to manage workflows, compliance, and measurement for customer references.
Plan and execute database migrations, data transformations, and system migrations safely with rollback strategies and data integrity validation. Use when migrating databases, transforming data schemas, moving between database systems, implementing versioned migrations, handling data transformations, ensuring data integrity, or planning zero-downtime migrations.