Run SQL queries against the WordPress development database. Use when querying database tables, inspecting Simple History events, checking WordPress data, or debugging database issues.

Access Human Metabolome Database (220K+ metabolites). Search by name/ID/structure, retrieve chemical properties, biomarker data, NMR/MS spectra, pathways, for metabolomics and identification.

Comprehensive toolkit for protein language models including ESM3 (generative multimodal protein design across sequence, structure, and function) and ESM C (efficient protein embeddings and representations). Use this skill when working with protein sequences, structures, or function prediction; designing novel proteins; generating protein embeddings; performing inverse folding; or conducting protein engineering tasks. Supports both local model usage and cloud-based Forge API for scalable inference.

Digital pathology image processing toolkit for whole slide images (WSI). Use this skill when working with histopathology slides, processing H&E or IHC stained tissue images, extracting tiles from gigapixel pathology images, detecting tissue regions, segmenting tissue masks, or preparing datasets for computational pathology deep learning pipelines. Applies to WSI formats (SVS, TIFF, NDPI), tile-based analysis, and histological image preprocessing workflows.

Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for large-scale datasets.

Write automated tests for features, validate functionality against acceptance criteria, and ensure code coverage. Use when writing test code, verifying functionality, or adding test coverage to existing code.

Transform, clean, reshape, and preprocess data using pandas and numpy. Works with ANY LLM provider (GPT, Gemini, Claude, etc.).

Create hierarchical project plans optimized for solo agentic development. Use when planning projects, phases, or tasks that Claude will execute. Produces Claude-executable plans with verification criteria, not enterprise documentation. Handles briefs, roadmaps, phase plans, and context handoffs.

Write Ruby and Rails code in DHH's distinctive 37signals style. Use this skill when writing Ruby code, Rails applications, creating models, controllers, or any Ruby file. Triggers on Ruby/Rails code generation, refactoring requests, code review, or when the user mentions DHH, 37signals, Basecamp, HEY, or Campfire style. Embodies REST purity, fat models, thin controllers, Current attributes, Hotwire patterns, and the "clarity over cleverness" philosophy.

Execute Codex CLI for code analysis, refactoring, and automated code changes. Use when you need to delegate complex code tasks to Codex AI with file references (@syntax) and structured output.

Laboratory automation toolkit for controlling liquid handlers, plate readers, pumps, heater shakers, incubators, centrifuges, and analytical equipment. Use this skill when automating laboratory workflows, programming liquid handling robots (Hamilton STAR, Opentrons OT-2, Tecan EVO), integrating lab equipment, managing deck layouts and resources (plates, tips, containers), reading plates, or creating reproducible laboratory protocols. Applicable for both simulated protocols and physical hardware control.

This skill provides symbol-level code understanding and navigation using Language Server Protocol (LSP). Enables IDE-like capabilities for finding symbols, tracking references, and making precise code edits at the symbol level.

Process-based discrete-event simulation framework in Python. Use this skill when building simulations of systems with processes, queues, resources, and time-based events such as manufacturing systems, service operations, network traffic, logistics, or any system where entities interact with shared resources over time.

Manage Model Context Protocol (MCP) servers - discover, analyze, and execute tools/prompts/resources from configured MCP servers. Use when working with MCP integrations, need to discover available MCP capabilities, filter MCP tools for specific tasks, execute MCP tools programmatically, access MCP prompts/resources, or implement MCP client functionality. Supports intelligent tool selection, multi-server management, and context-efficient capability discovery.

Keeps IdeaVim documentation in sync with code changes. Use this skill when you need to verify documentation accuracy after code changes, or when checking if documentation (in doc/, README.md, CONTRIBUTING.md) matches the current codebase. The skill can work bidirectionally - from docs to code verification, or from code changes to documentation updates.

Write docstrings for PyTorch functions and methods following PyTorch conventions. Use when writing or updating docstrings in PyTorch code.

Generate or edit images using AI models (FLUX, Gemini). Use for scientific illustrations, diagrams, schematics, infographics, concept visualizations, and artistic images. Supports image editing to modify existing images (change colors, add/remove elements, style transfer). Useful for figures, posters, and visual explanations.

Framework for computational fluid dynamics simulations using Python. Use when running fluid dynamics simulations including Navier-Stokes equations (2D/3D), shallow water equations, stratified flows, or when analyzing turbulence, vortex dynamics, or geophysical flows. Provides pseudospectral methods with FFT, HPC support, and comprehensive output analysis.

This skill should be used when converting academic papers into promotional and presentation formats including interactive websites (Paper2Web), presentation videos (Paper2Video), and conference posters (Paper2Poster). Use this skill for tasks involving paper dissemination, conference preparation, creating explorable academic homepages, generating video abstracts, or producing print-ready posters from LaTeX or PDF sources.

Create and manage Claude Code skills in HASH repository following Anthropic best practices. Use when creating new skills, modifying skill-rules.json, understanding trigger patterns, working with hooks, debugging skill activation, or implementing progressive disclosure. Covers skill structure, YAML frontmatter, trigger types (keywords, intent patterns), UserPromptSubmit hook, and the 500-line rule. Includes validation and debugging with SKILL_DEBUG. Examples include rust-error-stack, cargo-dependencies, and rust-documentation skills.