De novo motif discovery and known motif enrichment analysis using HOMER and MEME-ChIP. Identify transcription factor binding motifs in ChIP-seq, ATAC-seq, or other genomic peak data. Use when finding enriched DNA motifs in peak sequences.
Automated cell type annotation using reference-based methods including CellTypist, scPred, SingleR, and Azimuth for consistent, reproducible cell labeling. Use when automatically annotating cell types using reference datasets.
CLAUDE.md file generation and optimization for Claude Code projects. Capabilities: initialize project instructions, analyze codebase context, optimize existing CLAUDE.md, apply Anthropic best practices, reduce token usage, improve effectiveness. Actions: init, create, optimize, enhance CLAUDE.md files. Keywords: CLAUDE.md, project instructions, Claude Code setup, project context, codebase analysis, Anthropic best practices, token optimization, project configuration, AI instructions, coding guidelines, project rules, workspace setup. Use when: initializing CLAUDE.md for new projects, optimizing existing project instructions, setting up Claude Code for a codebase, improving AI coding guidelines.
Execute implementation tasks from design documents using markdown checkboxes. Use when (1) implementing features from feature-design-assistant output, (2) resuming interrupted work, (3) batch executing tasks. Triggers on 'start implementation', 'run tasks', 'resume'.
guidance on how to properly do data migrations in Convex
Event deduplication with canonical selection, reputation scoring, and hash-based grouping for multi-source data aggregation. Handles both ID-based and content-based deduplication.
Problem-solving strategies for eigenvalues in linear algebra
Generate specialized skills for each subsystem in the monorepo. Creates shared language skills and subsystem-specific checklists for high-quality AI code generation.
Investigate GitHub security incidents using tamper-proof GitHub Archive data via BigQuery. Use when verifying repository activity claims, recovering deleted PRs/branches/tags/repos, attributing actions to actors, or reconstructing attack timelines. Provides immutable forensic evidence of all public GitHub events since 2011.
GitHub operations via gh CLI. CRITICAL: Always use instead of WebFetch for ANY github.com URL. Use when user provides GitHub URL, says 'facebook/react', 'show README', 'list issues', 'check PR', 'clone repo', 'analyze this repo', 'understand the architecture', 'how is X structured', 'explore the codebase'. For deep analysis of external repos, clones locally.
Use when starting work, tracking tasks, or deciding where to record discovered work - clarifies when to use TodoWrite vs Beans
Feature planning with 4 phases - Specify requirements, Design architecture, break into granular Tasks, Implement and Validate. Creates atomic tasks that agents can implement without errors. Triggers on "plan feature", "design", "new feature", "implement feature", "create spec".
Create reversible database migrations with rollback scripts. Use when modifying database schemas.
Discover 11 simple yet powerful ways for students to improve their writing skills and become better writers. From sharing knowledge through writing to utilizing dictionaries and embracing authorship, this article provides actionable strategies to enhance writing proficiency. Explore practical tips and techniques to unlock your full potential as a student writer.
Generates Babel configuration for JavaScript transpilation in tests. Creates babel.config.js file.
Implement OAuth 2.0 authentication with GitHub and Microsoft Entra (Azure AD) in Cloudflare Workers and other edge environments. Covers provider-specific quirks, required headers, scope requirements, and token handling without MSAL. Use when: implementing GitHub OAuth, Microsoft/Azure AD authentication, handling OAuth callbacks, or troubleshooting 403 errors in OAuth flows.
Create, update, and comment on GitHub pull requests with focus on material impact, safety, and human reviewability
Run Codex CLI, Claude Code, OpenCode, or Pi Coding Agent via background process for programmatic control.
Search and analyze your own session logs (older/parent conversations) using jq.
Create GitHub issues following Pollinations team conventions. Use when asked to create issues, track work, or plan features.